This background of study by exam result of student to material human respiratory academic year 2017/2018. This study of class action is purpose to improve study result of students with using colaboration picture media with experiment result study in learning process Biology in XI MIPA 3 second semester in SMA N 2 Pangkalpinang academic year 2018/2019. After apply colaboration picture media with experiment method the result study of student have increasing. This study is doing into two cycles with total 37 students which are boys 14 and girls 23. Data collecting is using evaluate every cycle and observe to student as long as learning process. The student that has succes reach in this evaluation are students have the same minimal mark or above value standard which is 73. On cycle 1 there are 37 students 23 students get score in value standard and above value standard with average mark 72,03 with percentage 62,16%. The result of the test cycle 2 all of 37 students get in value standard and above value standard with average mark 83,85. This is prove that colaboration picture media with experiment method in Biology for human respiratory can increase result students’ learning for XI MIPA 3 in SMA N 2 Pangkalpinang.